Endocrine Abstracts

Introduction: Vitamin D (VD) deficiency affects many autoimmune disorders requiring steroid therapy. In contrast to glucocorticoid immune suppressive doses for autoimmune diseases, patients with Addison’s disease (AD) require physiological replacement. There is growing evidence of a cross-talk between glucocorticoids (GC) and VD. However, VD’s interaction with the GC pathway remains poorly understood.Methods: To explore this issue, CD14+</...

The treatment with multi kinase inhibitors (MKI) under clinical trials due to advanced thyroid cancer (TC) may postpone moving on the patients with advanced disease to the palliative care stage. However, chronic and escalating somatic symptoms during the treatment may promote the appearance of depressive reactions. It can be expected that a cognitive image of the disease, as a collection of subjective beliefs concerning patient’s own illness and treatment, will be an impo...